In this article Dr Giovanni Mosti, director, Department of Angiology, Clinica MD Barbantini, Lucca, Italy and president, International Compression Club examines current guidelines and best practice statements for the treatment and management of chronic venous leg ulcers (VLUs). He talks about the effectiveness of Gloria UlcerKit PRO which was evaluated in 500 patients with venous disease (Mosti, 2014).